Antimicrobial wound gel
SurgihoneyRO™ is a cutting-edge technology, an antimicrobial wound gel utilising bio-engineered honey to deliver Reactive Oxygen®.
Effective against multi-drug resistant microorganisms commonly found in chronic wounds1.
For more detailed information, please visit www.surgihoneyro.com
SurgihoneyRO™ provides enhanced healing and a powerful antimicrobial action to reduce the microbial load thus removing the barriers to wound healing. Unlike other medical grade honeys, SurgihoneyRO™ has been bioengineered to enhance and precisely control its antimicrobial potency.
Benefits of SurgihoneyRO™
Benefits of SurgihoneyRO™ natural honey base
SHOW REFERENCES
SurgihoneyRO™ is a single patient multi-use product which provides a clinically and cost-effective treatment regime and once opened may be used for up to 28 days.
SurgihoneyRO™ may be use for infected wounds through to healing.
1. Perfectus Biomed, data on file 2018
When SurgihoneyRO™ comes into contact with moisture, Reactive Oxygen® is instantly released and sustained for over 72 hours10.
SurgihoneyRO™ has all the natural healing-inducing, desloughing and tissue regenerative properties of the honey carrier, but it has been bioengineered to delivery precisely controlled level of Reactive Oxygen®.
SurgihoneyRO™ is a fast acting, effective antimicrobial.
SurgihoneyRO™ not only inhibits but also kills microbes at concentrations 10-1000 fold below those that are likely to be achieved in topical treatment. The speed of cidal activity is shown by the time-kill curves to be extremely rapid11.
SHOW REFERENCES
10. Kwakman PH, te Velde AA, de Boer L et al (2011) Two major medicinal honeys have different mechanisms of bactericidal activity. PLoS One 6(3): e17709.
11. Wounds UK (2013) Best Practice Statement. The use of tropical antimicrobial agents in wound management (third edition). London: Wounds UK.
SurgihoneyRO™ is supported by in vitro and clinical studies and has recently been recommended for use by Public Health England. Public Health England’s guidance on common infections recognises SurgihoneyRO™ as a treatment for venous leg ulcers to reduce bacterial load and infection2 explaining it could cut unnecessary antibiotic prescribing.
Below is a case study of a 91 year old lady, who used SurgihoneyRO™ for 14 days to treat a long term leg ulcer.
Key clinicals
Stephens, C.
Clinical Evaluation of 54 Patients in the UK of a Bioengineered Reactive Oxygen® Wound Gel in the Treatment and Management of Wound Infection.
Wounds UK, 2019, poster
Filipini, R.
H₂0₂ (SurgihoneyRO™) – Fast effective autolytic debridement and healing in long standing infected chronic wounds
TVS, 2019, Poster
Clarke, L.
The evaluation of SurgihoneyRO™ in the treatment of chronic wounds with suspected biofilms
Wounds UK, 2018, 14(5)
Dryden, M., Dickinson, A., Hudgell, L., Brooks, J., Saeed, K. and Cutting, K.F.
A multi-centre clinical evaluation of SurgihoneyRO™ in 114 wounds
Journal of Wound Care, 2016, 25(3)
Public Health England
Management and treatment of common infections
Antibiotic guidance for primary care: For consultation and local adaptation
(See Page 66 for SurgihoneyRO™ recommendation)
Public Health England, October, 2018
Dryden, M., Goddars, C., Madadi, A. et al
Using antimicrobial SurgihoneyRO™ to prevent caesarean wound infection
British Journal of Midwifery, 2014, 22(1)
Dryden, M., Tawse, C., Adams, J., et al.
The use of SurgihoneyRO™ to prevent or eradicate bacterial colonisation in dressing oncology long vascular lines
Journal of Wound Care, 2014
In Vitro studies
Author(s)
Title
Publication
Thomas, H., Davies, L. and Westgate, S.J.
Treatment of World Health Organisation priority pathogens using an antimicrobial wound gel
Wounds UK, 2018
Thomas, H., Davies, L. and Westgate, S.J.
A topical antimicrobial wound gel to treat multi-drug resistant pathogens in wound care
Wounds UK, 2018
Davies, L., Thomas, H. and Westgate, S.
Multi-Species Biofilm Disruption by Two Wound Care Products Using a Colony Drip Flow Model
TVS conference, 2018
Halstead, F.
Use of an engineered honey to eradicate pre-formed biofilms of important wound pathogens: an in vitro study
Journal of Wound Care, 2017, 26(7)
Halstead, F.
In vitro activity of an engineered honey, medical-grade honeys, and antimicrobial wound dressings against biofilm-producing clinical bacterial isolates
Journal of Wound Care, 2016, 25(2)
Cooke, J.
The antimicrobial activity of prototype modified honeys that generate reactive oxygen species (ROS) hydrogen peroxide
BMC Research Notes, 2015, 8(20)
Dryden, M.
Bioengineered honey: in vitro antimicrobial activity of a novel topical wound care treatment
Journal of Global Antimicrobial Resistance & Journal of Antimicrobial Chemotherapy, 2014
1. Perfectus Biomed, data on file 2018
2. Public Health England: Management and treatment of common infections: Antibiotic guidance for primary care: for consultation and local adaptation.
SHOW REFERENCES
SurgihoneyRO™ is indicated for infected wounds, chronic and acute wounds through to wound healing.
Chronic wounds including:
Acute wounds including:
Residual wound gel can be removed during the normal wound cleansing regime.
It is recommended to apply SurgihoneyRO™ once immediately after closure to assist healing and as an infection prevention measure. For surgical wounds at high risk of infection, e.g. abdominal surgical sites, continue to apply SurgihoneyRO™ at each dressing change.
It is recommended that SurgihoneyRO™ is applied every 72 hours (three days) and more frequently in critical wound infections to maximise effect. SurgihoneyRO™ may be used under compression bandaging for up to 7 days however potency will decrease after day 3.
Click on the image below to view the FAQs
Size | Product code | PIP code | NHS code | |
---|---|---|---|---|
SurgihoneyRO™* | 20g tube | RO151247 | 407-1205 | ELZ1262 |
SurgihoneyRO™* | 50g tube | RO151248 | 407-1213 | ELZ1267 |
*SurgihoneyRO™ is single patient, multi-use and once opened can be used for up to 28 days.
Perfectus Biomed, data on file 2018
Delivering Innovation