MIST Therapy is low energy, low intensity ultrasound delivered through a saline mist to the wound bed. This painless, non-contact, non-thermal energy results in four key aspects of wound healing:
MIST therapy is indicated for all wound types including chronic wounds, burns and post surgical wounds. MIST Therapy promotes wound healing through cleansing and maintenance debridement by the removal of yellow slough, fibrin, tissue, exudate and bacteria.
In a randomised, double blind, controlled multi-centre study on 133 diabetic foot ulcer patients 41% of wounds were healed after 12 weeks compared to 14% in the control group.
In a 51 patient study with chronic foot and leg ulcerations, a 94% wound volume reduction was observed in 5.5 weeks compared to 37.3% over a 9.8 week period with standard care.
In a 70 patient study with ischaemic wounds, 63% of patients treated with MIST achieved greater than 50% wound healing at 12 weeks compared to 29% with standard care.
*Clinical papers available on request
MIST Therapy has an anti-inflammatory effect in wounds with chronic inflammation. The inflammatory cells response to MIST Therapy also results in the production of chemical mediators that activate fibroblasts. Fibroblasts stimulated by ultrasound exhibit earlier release of growth factors.
Bacterial cells are more rigid and susceptible to micromechanical stress, in many cases when treated with MIST Therapy the membrane fractures and the cell dies. MIST Therapy has been shown to reduce a wide range of bacteria including MRSA, VRE and Pseudomonas.
Ultrasound provides the benefits of vasodilation of the capillaries surrounding the wound bed which increases circulation leading to the stimulation of new capillaries on a micro level.
The mist of saline propelled by the ultrasound waves bathes and cleanses the wound. When coupled with the vibration effect of the ultrasound, slough is broken up and effectively washed away. This is a gentle form of debridement that is painless to the patient.
MIST Therapy addresses barriers to healing by stimulating the wound environment and actively impacting the wound bed.