Application Guide

Hyiodine is a viscous solution (gel) composed of hyaluronic acid, iodine (0.1%) and potassium iodide providing an optimum moist wound environment which directly assists the wound healing process.

Hyaluronic acid is a natural part of the body and plays a key role in the tissue repair process, the iodine complex preserves the hylauronic acid from degradation. Hyiodine promotes healing in all wound types especially hard to heal wounds.

Where can Hyiodine be used?

yes Fistulae & sinuses yes Pressure ulcers yes Granulating tissue
yes Cavity wounds yes Infected wounds* yes Re-epithelialising tissue
yes Diabetic foot ulcers yes Sloughy tissue yes Highly exuding wounds
yes Leg ulcers yes Skin grafts* yes Dry wounds
yes Surgical dehiscence no Fungating wounds no Black necrosis

*see instructions for use

Do's and Don'ts

To ensure optimum results from Hyiodine follow the guidance below:

Initial treatment
yes DO change the dressing within the first 24 hours of application
yes DO continue to change the dressing daily until the wound inflammation subsides
yes DO change every 2-3 days once wound inflammation has subsided
yes DO use a Hyiodine saturated carrier (i.e. gauze, non-woven, alginate or hydrofibre)
yes DO use a foam carrier for non-infected shallow wounds only
yes DO ensure the dressing is placed within the wound margins
Infected wounds
yes DO apply daily for infected wounds
yes DO use in conjunction with systemic antibiotics for heavily infected / colonised wounds, however they are not required for MRSA infected wounds.
no DO NOT leave on infected wounds for more than 24 hours as the iodine will be consumed and so will the antimicrobial effect. If left in place for too long on infected wounds it may cause the infection to grow
Cavity wounds
yes DO fill with a carrier well saturated with Hyiodine as the fistula drain
yes DO apply directly into very small sinuses and cavities
no DO NOT force into or pack wounds too tightly
Leg Ulcers
yes DO apply a small amount directly to the wound and cover with a saturated carrier
yes DO change dressings daily for first week until inflammation subsides
no DO NOT use under tight bandaging i.e. four layer compression
Dry wounds
yes DO combine Hyiodine with an oily gauze or silicone dressing on dry wounds to prevent the Hyaluronic acid from drying out or use with a polyurethane foam carrier
High exuding wounds
yes DO apply with saturated carrier to ensure optimum coverage
yes DO use sorbion sachet S as a secondary dressing for moderately to highly exuding wounds
Skin Grafts
yes DO use to prepare the wound bed for skin grafts
yes DO use following 24 hours graft placement as Hyiodine may improve graft adhesion
no DO NOT use for at least 24 hours following graft placement as the iodine may damage the new graft

Applying Hyiodine:

In most instances a simple gauze or non-woven dressing may be used as a carrier for Hyiodine however alternatives such as an alginate or hydrofibre dressing may be utilised.

Hyiodine can be applied directly to the wound or indirectly via a sterile dressing:

  • Directly to the wound bed: Suitable for treating small wounds, surface defects and cavities via sterile syringe
  • Indirect application: Via a sterile dressing carrier is suitable for wounds more than 4cm in diameter

Applying Hyiodine to sterile gauze, non-woven, alginate or hydrofibre carrier for deep and infected wounds:

  • Draw the Hyiodine from the applicator via a sterile syringe
  • Use the recommended quantity of Hyiodine based on the size of the wound to gain optimum results
  • Ensure good saturation of the dressing (if no product can be squeezed out use more)
  • Apply Hyiodine within wound parameters
  • Retain with appropriate dressing/bandage
Hyiodine application diagrams

Applying Hyiodine to foam dressing for shallow non-infected wounds:

  • Cut the dressing to the shape of the wound
  • Use the recommended quantity of Hyiodine based on the size of the wound to gain optimum results
  • Cover wound contact side with Hyiodine
  • Retain with appropriate dressing/bandage

How much Hyiodine to use

Wound Size Recommended Quantity of Hyiodine
5 x 5cm (25cm2) 2ml
7.5 x 7.5cm 56cm2) 5ml
10 x 10cm (100cm2) 7-8 ml
12 x 12cm (144cm2) 11-12ml
15 x 15cm (225cm2) 18ml
20 x 20cm (400cm2) 32ml

Apply approximately 2ml for every 25cm2 wound area. Using less than the recommended quantity can reduce effectiveness and possibly cause adhesion to the wound.

Answers to frequently asked questions:

  • Hyiodine is a single patient, multi-use product;
  • Once opened the bottle should be stored in a refrigerator for up to 6 weeks and brought to room temperature before use to enable easy application;
  • Patients may be treated indefinitely with Hyiodine due to the low level of iodine;
  • Hyiodine has been used in clinical practice for over 5 years and on patients with known iodine allergies. No adverse effects or allergic reactions have been reported, however, exercise caution;
  • Hyiodine is NOT contraindicated for patients with thyroid problems however treatment should be discussed with a physician;
  • Hyiodine is NOT an antimicrobial dressing however due to the iodine contained within Hyiodine (0.1%) it may be used on infected wounds with daily dressing changes.

Please see product insert leaflet for full instructions in use.